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Minggu, 15 April 2012

Anatomi dan Fisiologi Sistem Endokrin



Anatomi dan Fisiologi Sistem Endokrin

Sistem endokrin, dalam kaitannya dengan sistem saraf, mengontrol dan memadukan fungsi tubuh. Kedua sistem ini bersama-sama bekerja untuk mempertahankan homeostasis tubuh. Fungsi mereka satu sama lain saling berhubungan, namun dapat dibedakan dengan karakteristik tertentu. Misalnya, medulla adrenal dan kelenjar hipofise posterior yang mempunyai asal dari saraf (neural). Jika keduanya dihancurkan atau diangkat, maka fungsi dari kedua kelenjar ini sebagian diambil alih oleh sistem saraf.

Sabtu, 14 April 2012

The Neurological System

The Neurological System

All of our body systems work in conjunction with each other and none are capable of working in isolation. The nervous system controls and coordinates the functioning of all other systems in response to our surroundings. Each stimulus or change in our environment is detected by our senses and messages are interpreted by the brain that in turn, sends directions to the various organs to respond and adapt according to the external conditions which affect our body.

Rabu, 11 April 2012

Lada (Latent Autoimmune Diabetes in Adults) or other type of diabetes

Latent Autoimmune Diabetes in Adults (LADA) is a form of autoimmune diabetes (type 1A diabetes) which is diagnosed in individuals who are older than the usual age of onset of type 1 diabetes (that is, over 30 years of age at diagnosis). Alternate terms that have been used for "LADA" include Late-onset Autoimmune Diabetes of Adulthood, "Slow Onset Type 1" diabetes, and sometimes also "Type 1.5 [Type one-and-a-half]" diabetes.

Often, patients with LADA are mistakenly thought to have type 2 diabetes, based on their age at the time of diagnosis. Such misdiagnosis is easy to make when the person is older, and initially responds to treatment with diabetes pills. It is now thought that perhaps twenty percent of patients with apparent Type 2 diabetes really have LADA. 

Patients with LADA do not have insulin resistance, as do people with Type 2. Also, positive antibody tests would help make the diagnosis of LADA in a person who might be suspected of having either LADA or Type 2. 

Some diabetes specialists feel that once LADA is diagnosed, it is important to promptly start the patient on insulin therapy (rather than using sulfonylureas or other diabetes pills), but it is unclear whether early treatment with insulin is beneficial for the remaining beta cells. 

Drug therapy to preserve insulin function in patients with LADA is being investigated.
Characteristics of LADA include:
  • Adult age at diagnosis (usually over 25 years of age)
  • Initial presentation masquerades as non-obese type 2 diabetes (does not present as diabetic ketoacidosis)
  • Initially can be controlled with meal planning with or without diabetes pills
  • Insulin dependency gradually occurs, frequently within months
  • Positive antibodies
  • Low C-peptide levels
  • Unlikely to have a family history of type 2 diabetes

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